Increased frequencies of CD8+ T lymphocytes recognizing wildtype p53derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants …

VR Cicinnati, X Zhang, Z Yu, S Ferencik… - … journal of cancer, 2006 - Wiley Online Library
cells but were inversely related to the T status of the tumor node … the existence of natural
immunosurveillance and tumor … a T cell response against WT p53 tumor antigen in patients with …

Profile of tumor antigen-specific CD8 T cells in patients with hepatitis B virus-related hepatocellular carcinoma

AJ Gehring, ZZ Ho, AT Tan, MO Aung, KH Lee, KC Tan… - Gastroenterology, 2009 - Elsevier
Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes
in peripheral blood correlate with presence of epitope loss tumor variants in patients with …

… T cells, tumor-associated macrophages, and regulatory T cells: association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer

CA Shah, KH Allison, RL Garcia, HJ Gray, BA Goff… - Gynecologic …, 2008 - Elsevier
cancer specimens with CD3 and CD8 (Intratumoral T cells (… alteration in ovarian cancer,
and the epitopes involved may … with presence of epitope loss tumor variants in patients with …

… the development of multi-epitope p53 cancer vaccines: an in vitro assessment of CD8+ T cell responses to HLA class I-restricted wild-type sequence p53 peptides

K Sakakura, K Chikamatsu, N Furuya, E Appella… - Clinical …, 2007 - Elsevier
CD8 + T cell precursors responsive to wt p53 epitopes were … No significant correlations
between CD8 + T cell responses to … lymphocyte clone recognizing a wild-type p53-derived

Tumor immunoediting and immunosculpting pathways to cancer progression

JM Reiman, M Kmieciak, MH Manjili… - Seminars in cancer …, 2007 - Elsevier
CD8 antibody depletion studies revealed that T lymphocytes … of p53 epitope-specific T
cells in lesions from patients with … of tumors with mutations in unique T cell epitopes that were …

Natural immunity to pluripotency antigen OCT4 in humans

KM Dhodapkar, D Feldman… - Proceedings of the …, 2010 - National Acad Sciences
… that T cells responding to peptide epitopes derived from … insulin (CD4/CD8, naive) was
feasible in T cells from healthy … for synthesis by using an epitope library fragment-generation …

Healthy individuals have T-cell and antibody responses to the tumor antigen cyclin B1 that when elicited in mice protect from cancer

LA Vella, M Yu, SR Fuhrmann… - Proceedings of the …, 2009 - National Acad Sciences
… We found no correlation between age and antibody levels in … experiment with purified CD8
+ T cells. After 10 days, the … peptides that could serve as T-cell epitopes. We asked whether …

… with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 …

IM Svane, AE Pedersen, JS Johansen… - Cancer Immunology …, 2007 - Springer
… on the cell surface, thereby, acting as tumor-associated epitopes. … studies have shown that
these wild-type p53 derived HLA-A2 … able to induce peptide specific CD8+ T cells [59] and the …

Adaptive immunity in hepatocellular carcinoma: prognostic and therapeutic implications

EM Fatourou, JS Koskinas - Expert Review of Anticancer Therapy, 2009 - Taylor & Francis
… -specific CD8 + T-cell responses revealed that CD8 + T cells … 46 epitope regions targeted by
AFP-specific CD8 + T cells were … and subdominant epitopes, melanoma tumor antigens and …

[HTML][HTML] Immune cell therapy for hepatocellular carcinoma

E Mizukoshi, S Kaneko - Journal of hematology & oncology, 2019 - Springer
… respective T cell epitopes, thus confirming the presence of T cell-… frequency and function of
NK cells in the peripheral blood … polyclonal T cells, both CD4 + and CD8 + T cells, and T cells